Healthy and Beauty. Finding of current life science experiment for human sustainability

This work is a collection of studies concerning human sustainability. We were proud for having Postgrad Colloquium 2019, Faculty of Health Sciences Universiti Sultan Zainal Abidin (UniSZA). It was held on 30th April 2019 at Academic Building UniSZA Main Campus Kuala Nerus, Terengganu, Malaysia. Total of 24 students including 15 students from Laboratory Based Research category and 9 students from Community Based Research category of Faculty Health Sciences and Faculty of Medicine were participated. We congratulated to the winners Omar Mahmoud Said Alshajrawi from Faculty of Medicine, Masters student for the Laboratory Based Research category and Mohd Ibrahim Abdullah from Faculty of Health Sciences, Doctorate student for the Community Based Research category. Both of you were pretty amazing. See again next year on 2020 to all researchers.

Inhaltsverzeichnis (Table of Contents)

• CLONING AND CHATACTERIZATION OF ALPHA ENOLASE GENE OF 6A STREPTOCOCCUS PNEUMONIA TOWARDS INDUCTION OF NETOSIS
• CONSTRUCTION OF FIVE EXPRESSION CLONES FOR PLASMODIUM KNOWLESI APICAL MEMBRANE ANTIGEN 1 (PKAMA1) USING PICHIA PASTORISEXPRESSION SYSTEM
• ISOLATION AND CHARACTERISTICS OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) AND METHICILLIN-SUSCEPTIBLE STAPHYLOCOCCUS AUREUS (MSSA) CLINICAL ISOLATES IN TERENGGANU
• RECOMBINANT PLASMODIUM KNOWLESI APICAL MEMBRANE ANTIGEN-1 (PKAMA1) EXPRESSION FOR THE PHAGE-DISPLAYED BINDING PEPTIDES SELECTION
• THE POTENTIAL EFFECT OF MALAYSIAN TRIGONA HONEY ON ENTERIC AND RESPIRATORY INFECTIONS BY USING WISTAR RATS MODEL
• THE GENOTYPIC AND ALLELIC CHARACTERIZATION OF VEGF PROMOTER (RS833061) VARIATION(S) AND THEIR ASSOCIATION WITH LIPID PROFILE, ANTHROPOMETRIC INDICES AND PHYSICAL ACTIVITY LEVELS AMONG MALAY OBESE
• ANTIBACTERIAL AND ANTIBIOFILM ACTIVITIES OF MALAYSIAN TRIGONA HONEY AGAINST PSEUDOMONAS AERUGINOSA AND STREPTOCOCCUS PYOGENES
• THE ROLE OF SOX 10 GENE IN THE DEVELOPMENT OF GLIOBLASTOMA MULTIFORME
• BIOFILM INHIBITION OF PERIODONTAL PATHOGEN BY PROBIOTIC STRAINS: GENE
• AN ASSOCIATION STUDY ON GENETIC POLYMORPHISM OF HBB GENE AMONG BETA-THALASEMIA MINOR PATIENTS
• BIOACTIVE COMPOUNDS, NUTRITIONAL VALUE, AND POTENTIAL HEALTH BENEFITS OF INDIGENOUS DURIAN (DURIO ZIBETHINUS MURR.): A REVIEW
• UNRAVELLING THE EFFECTS OF SOLUBLE DIETARY FIBRE SUPPLEMENTATION ON ENERGY INTAKE AND PERCEIVED SATIETY IN HEALTHY ADULTS: EVIDENCE FROM SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMISED-CONTROLLED TRIALS
• DETERMINATION OF SOX GENE EXPRESSION IN BRAIN TUMOR IN EAST COAST MALAYSIA
• GENETIC ASSOCIATION OF VARIATIONS IN HIF1 (RS11549465) AND NFKB1 (RS28362491) WITH ANTHROPOMETRIC INDICES AND LIPID PROFILE IN MALAY OBESE ATTRIBUTES
• IN VITRO ANTIBACTERIAL PROPERTIES OF ETLINGERA ELATIOR FLOWER EXTRACTS AGAINST ACNE-INDUCING BACTERIA: PROPIONIBACTERIUM ACNES AND STAPHYLOCOCCUS AUREUS
• THE EFFECTS OF CALORIE RESTRICTION ON COGNITIVE RECOVERY AMONG TRAUMATIC BRAIN INJURY PATIENTS
• STUDY PROPOSAL: ASSOCIATION BETWEEN DIETARY PATTERNS AND CORONARY HEART DISEASE (CHD) RISK FACTORS AMONG MALAYSIAN POPULATION
• PREVALENCE OF LATENT TUBERCULOSIS INFECTION AND ITS ASSOCIATED FACTORS AMONG DIABETIC PATIENTS AT PRIMARY HEALTH CARE IN TERENGGANU
• PREVALENCE OF CYBERBULLYING VICTIMS AND ITS ASSOCIATED FACTORS AMONG FORM 2 AND FORM 4 STUDENTS IN KUALA TERENGGANU, MALAYSIA
• STUDY PROPOSAL: DETERMINATION OF PROANTHOCYANIDIN CONTENTS IN MELON MANIS TERENGGANU (CUCUMIS MELO L.) AND THERAPEUTIC APPLICATION AMONG KNEE OSTEOARTHRITIS PATIENTS
• THE RELATIONSHIP OF FRUIT INTAKE WITH BRAIN DERIVED NEUROTROPHIC FACTOR (BDNF) PROTEIN LEVEL AMONG ADOLESCENTS IN TERENGGANU
• STUDY PROPOSAL: PREVALENCE AND RISK FACTORS OF HYPERTENSION AMONG ADULTS IN TERENGGANU'S FELDA
• THE CONCEPT OF WELL-BEING AMONG HEMODIALYSIS CHRONIC KIDNEY PATIENTS: A CORRELATION STUDY
• STUDY PROPOSAL: DEVELOPMENT OF DIETARY RISK CALCULATOR TO PREDICT CORONARY

Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)

This compilation of research studies focuses on exploring various aspects of human health and well-being, particularly within the context of Malaysian populations. The research aims to contribute to the understanding of disease mechanisms, identify potential therapeutic interventions, and promote overall health and sustainability.

• Investigating the role of genes and genetic variations in various health conditions, including obesity, diabetes, and cancer.
• Exploring the potential benefits of natural remedies, such as Malaysian Trigona honey, for treating infections and other health issues.
• Analyzing the impact of dietary factors on health, including the effects of soluble dietary fiber supplementation on energy intake and satiety, and the association between dietary patterns and coronary heart disease risk factors.
• Examining the prevalence and associated factors of various health conditions, including latent tuberculosis infection, cyberbullying, and hypertension.
• Developing novel therapeutic approaches and interventions, such as the construction of expression clones for Plasmodium knowlesi apical membrane antigen 1 (PkAMA1) for potential vaccine development.

Zusammenfassung der Kapitel (Chapter Summaries)

• CLONING AND CHATACTERIZATION OF ALPHA ENOLASE GENE OF 6A STREPTOCOCCUS PNEUMONIA TOWARDS INDUCTION OF NETOSIS: This study investigates the role of the enol gene of S.pneumoniae in the induction of neutrophil extracellular traps (NETs), a critical defense mechanism against bacterial infection. The study aims to understand how mutations in the enol gene affect NETosis and bacterial dissemination.
• CONSTRUCTION OF FIVE EXPRESSION CLONES FOR PLASMODIUM KNOWLESI APICAL MEMBRANE ANTIGEN 1 (PKAMA1) USING PICHIA PASTORISEXPRESSION SYSTEM: This study focuses on constructing expression clones for different regions of PkAMA1, a crucial protein involved in the parasite-host cell invasion mechanism of Plasmodium knowlesi, a potentially fatal malaria parasite. The study aims to develop a potential vaccine against this parasite.
• ISOLATION AND CHARACTERISTICS OF METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (MRSA) AND METHICILLIN-SUSCEPTIBLE STAPHYLOCOCCUS AUREUS (MSSA) CLINICAL ISOLATES IN TERENGGANU: This study investigates the prevalence and characteristics of MRSA and MSSA, two types of Staphylococcus aureus bacteria, in Terengganu, Malaysia. This information is crucial for understanding the spread of antibiotic resistance and developing effective treatment strategies.
• RECOMBINANT PLASMODIUM KNOWLESI APICAL MEMBRANE ANTIGEN-1 (PKAMA1) EXPRESSION FOR THE PHAGE-DISPLAYED BINDING PEPTIDES SELECTION: This study explores the use of phage-displayed binding peptides to identify potential targets for antimalarial drug development, specifically focusing on PkAMA1, a crucial protein involved in the invasion of red blood cells by Plasmodium knowlesi.
• THE POTENTIAL EFFECT OF MALAYSIAN TRIGONA HONEY ON ENTERIC AND RESPIRATORY INFECTIONS BY USING WISTAR RATS MODEL: This study investigates the potential therapeutic effects of Malaysian Trigona honey on enteric and respiratory infections using a Wistar rat model. The study aims to explore the antibacterial and anti-inflammatory properties of Trigona honey and its potential application in treating these infections.
• THE GENOTYPIC AND ALLELIC CHARACTERIZATION OF VEGF PROMOTER (RS833061) VARIATION(S) AND THEIR ASSOCIATION WITH LIPID PROFILE, ANTHROPOMETRIC INDICES AND PHYSICAL ACTIVITY LEVELS AMONG MALAY OBESE: This study investigates the association between genetic variations in the VEGF promoter and lipid profile, anthropometric indices, and physical activity levels among Malaysian obese individuals. The study aims to understand the role of genetic factors in obesity and related health conditions.
• ANTIBACTERIAL AND ANTIBIOFILM ACTIVITIES OF MALAYSIAN TRIGONA HONEY AGAINST PSEUDOMONAS AERUGINOSA AND STREPTOCOCCUS PYOGENES: This study examines the antibacterial and antibiofilm activities of Malaysian Trigona honey against Pseudomonas aeruginosa and Streptococcus pyogenes, two common bacterial pathogens. This research investigates the potential use of Trigona honey as a natural antimicrobial agent.
• THE ROLE OF SOX 10 GENE IN THE DEVELOPMENT OF GLIOBLASTOMA MULTIFORME: This study investigates the role of the SOX10 gene in the development of glioblastoma multiforme, a highly aggressive type of brain tumor. The research aims to understand the molecular mechanisms underlying tumor development and identify potential therapeutic targets.
• BIOFILM INHIBITION OF PERIODONTAL PATHOGEN BY PROBIOTIC STRAINS: GENE: This study explores the potential of probiotic strains to inhibit the formation of biofilms by periodontal pathogens, bacteria that contribute to gum disease. This research investigates the potential use of probiotics in preventing and treating periodontal disease.
• AN ASSOCIATION STUDY ON GENETIC POLYMORPHISM OF HBB GENE AMONG BETA-THALASEMIA MINOR PATIENTS: This study investigates the association between genetic variations in the HBB gene and the development of beta-thalassemia minor, a blood disorder. This research aims to understand the genetic basis of this condition and identify potential genetic markers for early diagnosis and treatment.
• BIOACTIVE COMPOUNDS, NUTRITIONAL VALUE, AND POTENTIAL HEALTH BENEFITS OF INDIGENOUS DURIAN (DURIO ZIBETHINUS MURR.): A REVIEW: This review article explores the bioactive compounds, nutritional value, and potential health benefits of Durian, a popular fruit in Malaysia. The review highlights the potential medicinal properties of Durian and its potential application in promoting health and well-being.
• UNRAVELLING THE EFFECTS OF SOLUBLE DIETARY FIBRE SUPPLEMENTATION ON ENERGY INTAKE AND PERCEIVED SATIETY IN HEALTHY ADULTS: EVIDENCE FROM SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMISED-CONTROLLED TRIALS: This systematic review and meta-analysis investigates the effects of soluble dietary fiber supplementation on energy intake and perceived satiety in healthy adults. The review aims to provide evidence-based recommendations for incorporating dietary fiber into a healthy diet.
• DETERMINATION OF SOX GENE EXPRESSION IN BRAIN TUMOR IN EAST COAST MALAYSIA: This study investigates the expression of SOX genes in brain tumors in the East Coast of Malaysia. The research aims to understand the role of these genes in brain tumor development and identify potential biomarkers for diagnosis and treatment.
• GENETIC ASSOCIATION OF VARIATIONS IN HIF1 (RS11549465) AND NFKB1 (RS28362491) WITH ANTHROPOMETRIC INDICES AND LIPID PROFILE IN MALAY OBESE ATTRIBUTES: This study investigates the association between genetic variations in HIF1 and NFKB1 genes and anthropometric indices and lipid profile in Malaysian obese individuals. The study aims to understand the role of genetic factors in obesity-related health conditions.
• IN VITRO ANTIBACTERIAL PROPERTIES OF ETLINGERA ELATIOR FLOWER EXTRACTS AGAINST ACNE-INDUCING BACTERIA: PROPIONIBACTERIUM ACNES AND STAPHYLOCOCCUS AUREUS: This study investigates the antibacterial properties of Etlingera elatior flower extracts against Propionibacterium acnes and Staphylococcus aureus, two bacteria commonly associated with acne. The study aims to explore the potential of this plant extract as a natural treatment for acne.
• THE EFFECTS OF CALORIE RESTRICTION ON COGNITIVE RECOVERY AMONG TRAUMATIC BRAIN INJURY PATIENTS: This study investigates the effects of calorie restriction on cognitive recovery among patients with traumatic brain injury. The study aims to understand the impact of nutritional interventions on brain function and recovery after injury.
• STUDY PROPOSAL: ASSOCIATION BETWEEN DIETARY PATTERNS AND CORONARY HEART DISEASE (CHD) RISK FACTORS AMONG MALAYSIAN POPULATION: This study proposal outlines a research plan to investigate the association between dietary patterns and coronary heart disease risk factors among the Malaysian population. The study aims to identify dietary factors that contribute to CHD risk and develop recommendations for dietary interventions to prevent this condition.
• PREVALENCE OF LATENT TUBERCULOSIS INFECTION AND ITS ASSOCIATED FACTORS AMONG DIABETIC PATIENTS AT PRIMARY HEALTH CARE IN TERENGGANU: This study investigates the prevalence of latent tuberculosis infection and its associated factors among diabetic patients in Terengganu, Malaysia. The study aims to understand the risk factors for tuberculosis infection in this population and develop strategies for early detection and treatment.
• PREVALENCE OF CYBERBULLYING VICTIMS AND ITS ASSOCIATED FACTORS AMONG FORM 2 AND FORM 4 STUDENTS IN KUALA TERENGGANU, MALAYSIA: This study investigates the prevalence of cyberbullying victims and its associated factors among secondary school students in Kuala Terengganu, Malaysia. The study aims to understand the extent of cyberbullying in this population and identify risk factors and protective factors against cyberbullying.
• STUDY PROPOSAL: DETERMINATION OF PROANTHOCYANIDIN CONTENTS IN MELON MANIS TERENGGANU (CUCUMIS MELO L.) AND THERAPEUTIC APPLICATION AMONG KNEE OSTEOARTHRITIS PATIENTS: This study proposal outlines a research plan to investigate the proanthocyanidin content of Melon Manis Terengganu, a local melon variety, and its potential therapeutic application in treating knee osteoarthritis. The study aims to explore the anti-inflammatory and analgesic properties of this melon and its potential use as a natural remedy for osteoarthritis.
• THE RELATIONSHIP OF FRUIT INTAKE WITH BRAIN DERIVED NEUROTROPHIC FACTOR (BDNF) PROTEIN LEVEL AMONG ADOLESCENTS IN TERENGGANU: This study investigates the relationship between fruit intake and brain-derived neurotrophic factor (BDNF) protein levels among adolescents in Terengganu, Malaysia. The study aims to understand the impact of fruit consumption on brain health and cognitive function in this population.
• STUDY PROPOSAL: PREVALENCE AND RISK FACTORS OF HYPERTENSION AMONG ADULTS IN TERENGGANU'S FELDA: This study proposal outlines a research plan to investigate the prevalence and risk factors for hypertension among adults in the Felda settlements in Terengganu, Malaysia. The study aims to identify factors that contribute to hypertension in this population and develop strategies for early detection and prevention.
• THE CONCEPT OF WELL-BEING AMONG HEMODIALYSIS CHRONIC KIDNEY PATIENTS: A CORRELATION STUDY: This study investigates the concept of well-being among hemodialysis chronic kidney patients, exploring the factors that contribute to their well-being and how these factors correlate with their overall health and quality of life.
• STUDY PROPOSAL: DEVELOPMENT OF DIETARY RISK CALCULATOR TO PREDICT CORONARY: This study proposal outlines a research plan to develop a dietary risk calculator to predict the risk of coronary heart disease based on dietary patterns and other risk factors. The study aims to provide a tool for individuals to assess their risk and make informed decisions about their diet and lifestyle.

Schlüsselwörter (Keywords)

This research compilation focuses on various aspects of human health and well-being, particularly within the Malaysian population. Key themes include the genetic basis of health conditions, natural remedies for infections and disease, the role of diet in health, the prevalence and factors associated with various health conditions, and the development of novel therapeutic approaches. Specific research focuses include the study of genes and genetic variations, the investigation of Malaysian Trigona honey, the analysis of dietary patterns and their impact on health, the prevalence and associated factors of diseases like tuberculosis, cyberbullying, and hypertension, and the development of potential vaccines and other therapeutic interventions. This research contributes to a broader understanding of human health and well-being, aiming to promote health and sustainability within the Malaysian population.

Details

• Note: 10.0
• Autor: Mohd Hilmi Abu Bakar (Herausgeber:in)
• Erscheinungsjahr: 2019
• Seiten: 27
• Katalognummer: V493733
• ISBN (eBook): 9783668995666
• ISBN (Buch): 9783668995673
• Sprache: Englisch
• Schlagworte: healthy beauty finding