Since the avian cancer virus experiment in 2011, scientists have confirmed seven different viruses that cause about ten to fifteen percent of human cancer globally. Notably, these distinct viruses have revealed unprecedented links between innate immunities as well as sensors and tumour suppressors, implying that they control both cancer and viral infections.
Apparently, these varied cancers remain to be a substantial health challenge, especially in developing economies, alongside the underserved and immuno-suppressed individuals in developed economies.
Among the several human tumour viruses evidenced by several scientists and scholars, this paper will explore the Epstein-Barr virus (EBV), the Hepatitis B virus (HBV) and the Human papilloma virus (HPV) along with their distinct ways by which they cause tumours.
Inhaltsverzeichnis (Table of Contents)
- Introduction
- Epstein-Barr virus (EBV)
- EBV Microbe Description
- EBV Disease Explanation
- Course of the EBV Infection
- Current Research and Future Research/Directions
- World Relevance
- Hepatitis B virus (HBV)
- HBV Microbe Description
- HBV Disease Explanation
- HBV Disease Course
- Interaction between HBV Microbe and Host
- HBV Current Research and Future Research/Directions
- Human papilloma virus (HPV)
- HPV Microbe Description
- HPV Disease Explanation
- HPV Disease Course
- HPV Current Research and Future Research/Directions
Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)
This paper aims to explore the distinct ways by which three human tumour viruses, Epstein-Barr virus (EBV), Hepatitis B virus (HBV), and Human papilloma virus (HPV), cause tumours.
- The role of viruses in causing cancer
- The mechanisms by which specific viruses like EBV, HBV, and HPV induce tumorigenesis
- Current and future research directions in understanding and treating viral-related cancers
- The global relevance of these viruses and their associated cancers
- The interaction between viruses and the host immune system in the context of cancer development
Zusammenfassung der Kapitel (Chapter Summaries)
Epstein-Barr virus (EBV)
This section delves into the characteristics of the Epstein-Barr virus (EBV), also known as human herpes virus 4 (HHV4). It discusses the virus's DNA genome, its ability to establish latency in B lymphocytes, and its association with various malignancies, including Burkitt's lymphoma, leiomyosarcomas, and post-transplant lymphoproliferative diseases. It also explores the course of EBV infection and the potential for immune therapy in treating EBV-linked tumors. The section concludes with a discussion on the global relevance of EBV and its impact in regions with high incidences of Burkitt's lymphoma and nasopharyngeal carcinoma.
Hepatitis B virus (HBV)
This section focuses on the Hepatitis B virus (HBV), a DNA virus that causes acute and chronic hepatitis. It examines the HBV virion's structure, its genome, and the mechanism by which it causes hepatocellular carcinoma. The section details the course of HBV infection, highlighting the appearance of surface antigen, DNA polymerase activity, and core antibody in the serum. It also discusses the interaction between HBV and the host immune system, emphasizing the role of antibody and cell-mediated immune responses. The section concludes with an overview of current and future research directions in treating HBV-related cancers, including traditional surgical approaches and newer non-surgical options.
Human papilloma virus (HPV)
This section delves into the Human papilloma virus (HPV), a DNA virus that is associated with cervical cancer and other malignancies. It explains the different types of HPV, the HPV genome, and the mechanisms by which HPV infects cells and causes disease. The section explores the various stages of HPV infection, highlighting the progression from asymptomatic infection to precancerous lesions and ultimately to invasive cancer. It also discusses the importance of HPV vaccination in preventing cervical cancer and other HPV-related diseases.
Schlüsselwörter (Keywords)
The key themes and concepts explored in this paper include: viruses, tumorigenesis, EBV, HBV, HPV, cancer, infectious mononucleosis, Burkitt's lymphoma, nasopharyngeal carcinoma, hepatitis, hepatocellular carcinoma, cervical cancer, HPV vaccination, immune system, latency, lytic cycle, DNA replication, viral genome, oncogenesis, treatment options, global relevance, and research directions.
- Quote paper
- Business Administrator Mutinda Jackson (Author), 2018, The different ways in which viruses cause tumors, Munich, GRIN Verlag, https://www.hausarbeiten.de/document/429538
