Herbal drug product has a special place in the world of pharmaceuticals. Terminalia chebula is a deciduous tree, used in traditional medicines. It is reported to contain various bio chemical compounds such as tannins, chebulinic acid, ellagic acid, gallic acid, punicalagin, flavonoids etc. It has been reported as antioxidant, antidiabetic, antibacterial, antiviral, antifungal, anticancerous, antiulcer, antimutagenic, wound healing activities etc.
The optimization of physico-chemical parameters like effects of different solvents, soaking time, extraction time with hexane, particle size, different solvent percentages, different volumes of hexane with ethanol and methanol as solvents and pH for the extraction of Total Phenolic Content, Chebulinic acid and Quercetin were studied. The extraction was carried out by employing various organic solvents using Soxhlet extractor method. Ethanol was found to be the best solvent for the extraction of Chebulinic acid from Terminalia chebula species. Soxhlet extractor was carried out using ethanol at different extraction times to verify the mathematical model proposed in this work.
The optimization of physico-chemical parameters required for obtaining the highest production of Chebulinic acid using Baker’s yeast (Saccharomyces cerevisia.Among the extraction process (Batch, Soxhlet& Fermentation process) the highest Chebulinic acid production was obtained from fermentation process. The partition coefficient for fermentation, soxhlet & batch extraction were found to be 3.83, 2.0 & 0.64.
The extraction of Chebulinic acid from Terminalia chebula by Soxhlet extraction and purify the Chebulinic acid by using Column chromatography. Chebulinic acid showed many bioactivities including inhibition of cancer cell growth, inhibiting the contractile responses of cardiovascular muscles, anti-fungal, anti-bacterial activities etc. Finally the Chebulinic acid extraction from Terminalia chebula plays a vital role in medicine, biotechnology and various pharmacological activities.
Inhaltsverzeichnis (Table of Contents)
- Introduction
- Andhra University Organizational Profile
- Department of Chemical Engineering
Zielsetzung und Themenschwerpunkte (Objectives and Key Themes)
This project report details the studies on chebulinic acid extraction from Terminalia chebula species. The primary objective is to fulfill the requirements for a Master of Technology degree in Biotechnology.
- Chebulinic acid extraction techniques
- Analysis of Terminalia chebula as a source of chebulinic acid
- Biotechnology applications of chebulinic acid
- Andhra University's role in chemical engineering and biotechnology research
Zusammenfassung der Kapitel (Chapter Summaries)
Introduction: This section provides background information on the project, including its purpose and the methodology used to study chebulinic acid extraction from Terminalia chebula. It sets the stage for the detailed exploration of the extraction process and the analysis of the resulting product. The introduction emphasizes the significance of chebulinic acid and its potential applications in various fields, thus highlighting the importance of the research undertaken in this project.
Andhra University Organizational Profile: This chapter offers a detailed overview of Andhra University, focusing on its history, achievements, and contributions to the field of education and research. It showcases the university's long-standing reputation as a leading institution in India, highlighting its diverse academic programs and research facilities. The description of the university's commitment to teaching, research, and community development emphasizes its crucial role in the project's context, establishing the backdrop for the academic rigor and resources that supported the research. It also outlines the various departments and research centers within the university, illustrating the multifaceted nature of the institution and its extensive resources available to support research initiatives like this project.
Department of Chemical Engineering: This section specifically focuses on the Department of Chemical Engineering at Andhra University, emphasizing its history, its pioneering role in chemical engineering education in India, and its diverse range of courses and specializations. It highlights the department's contribution to the broader field and its commitment to innovation and research, underscoring the significance of the departmental expertise in facilitating the research on chebulinic acid extraction. The summary contextualizes the project within the department's expertise and research strengths, illustrating the department's contribution to the project's success. The overview of the department's infrastructure and its commitment to teaching excellence further supports the project's credibility and its integration within a well-established research environment.
Schlüsselwörter (Keywords)
Chebulinic acid, Terminalia chebula, extraction, biotechnology, Andhra University, chemical engineering, research project, Master of Technology.
Frequently Asked Questions: Chebulinic Acid Extraction from Terminalia chebula
What is the main topic of this project report?
This project report details the studies on chebulinic acid extraction from Terminalia chebula. The primary objective is to fulfill the requirements for a Master of Technology degree in Biotechnology.
What are the key themes explored in the report?
The report explores chebulinic acid extraction techniques, analyzes Terminalia chebula as a source of chebulinic acid, examines biotechnology applications of chebulinic acid, and discusses Andhra University's role in chemical engineering and biotechnology research.
What is included in the Table of Contents?
The table of contents includes an Introduction, a profile of Andhra University, and a description of the Department of Chemical Engineering.
What is the purpose of the "Andhra University Organizational Profile" section?
This section provides an overview of Andhra University, highlighting its history, achievements, contributions to education and research, and its various departments and research centers. It establishes the context of the research within a reputable academic institution.
What is the significance of the "Department of Chemical Engineering" section?
This section focuses on the Department of Chemical Engineering at Andhra University, emphasizing its history, contributions to chemical engineering education, diverse specializations, and research strengths. It highlights the departmental expertise that supported the chebulinic acid extraction research.
What information is provided in the chapter summaries?
The chapter summaries provide concise overviews of the Introduction, Andhra University Organizational Profile, and Department of Chemical Engineering sections, highlighting the key content and purpose of each chapter.
What are the key words associated with this project?
The keywords include Chebulinic acid, Terminalia chebula, extraction, biotechnology, Andhra University, chemical engineering, research project, and Master of Technology.
What is the overall goal of this project?
The overarching goal is to conduct research on chebulinic acid extraction from Terminalia chebula and contribute to the body of knowledge in biotechnology and chemical engineering.
- Quote paper
- Surya Prakash (Author), Dr. Meena Vangalapati (Author), 2012, Studies on Chebulinic Acid Extraction from Terminalia chebula species, Munich, GRIN Verlag, https://www.hausarbeiten.de/document/231724